Coronavirus medicine update: Decade-old Actemra emerges as hope for COVID-19 victims

News Network
March 4, 2020

Beijing/Zurich, Mar 4: China has approved the use of Swiss drugmaker Roche's anti-inflammation drug Actemra for patients who develop severe complications from the coronavirus as it urgently hunts for new ways to combat the deadly infection that is spreading worldwide.

China is hoping that some older drugs could stop severe cytokine release syndrome (CRS), or cytokine storms, an overreaction of the immune system which is considered a major factor behind catastrophic organ failure and death in some coronavirus patients.

Actemra, a biologic drug approved in 2010 in the United States for rheumatoid arthritis (RA), inhibits high Interleukin 6 (IL-6) protein levels that drive some inflammatory diseases.

China's National Health Commission said in treatment guidelines published online on Wednesday that Actemra can now be used to treat coronavirus patients with serious lung damage and high IL-6 levels.

Separately, researchers in the country are testing Actemra, known generically as tocilizumab, in a clinical trial expected to include 188 coronavirus patients and running until May 10.

Roche, which donated 14 million yuan ($2.02 million) worth of Actemra during February, said the trial was initiated independently by a third party with the aim of exploring the efficacy and safety of the drug in coronavirus patients with CRS.

It added that there was currently no published clinical trial data on the drug's safety or efficacy against the virus.

More than 3,000 people have died and 93,000 have been infected by the novel coronavirus thought to have originated in Wuhan, China, before spreading to around 90 countries including the United States, Italy, Switzerland, France and Germany.

The Swiss company, for which China is its No. 2 market behind the United States, also makes diagnostic gear to detect the coronavirus.

Since Actemra's approval a decade ago, it has become a go-to drug against other inflammatory conditions, including cytokine storms in cancer patients receiving cell therapies from Novartis and Gilead Sciences.

In 2012 it helped save the life of a young U.S. girl, the first child to be treated for leukaemia with Novatis' Kymriah, from a post-treatment rush of IL-6.

Priced at between $20-30,000 annually for RA according to SSR Health, Roche's medicine is also used for rare juvenile arthritis and giant cell arteritis, or inflammation of the blood vessels.

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News Network
November 26,2025

Mangaluru, Nov 26: Assembly Speaker and local MLA U.T. Khader has initiated a high-level push to resolve one of Mangaluru’s longest-standing traffic headaches: the narrow, high-density stretch of National Highway-66 between Nanthoor and Talapady.

He announced on Tuesday that a formal proposal has been submitted to the Union Ministry of Road Transport and Highways (MoRTH) seeking approval to prepare a Detailed Project Report (DPR) for the widening of this crucial corridor.

The plan specifically aims to expand the existing 45-meter road width to a full 60 meters, coupled with the construction of dedicated service roads. Khader highlighted that land for a 60-meter highway was originally acquired during the initial four-laning project, but only 45 meters were developed, leading to a perpetual bottleneck.

"With vehicle density rising sharply, the expansion has become unavoidable," Khader stated, stressing that the upgrade is essential for ensuring smoother traffic flow and improving safety at the city's main entry and exit points.

The stretch between Nanthoor and Talapady is a vital link on the busy Kochi-Panvel coastal highway and connects to major city junctions. The move to utilize the previously acquired land for the full 60-meter width is seen as a necessary measure to catch up with the region's rapid vehicular growth and prevent further traffic gridlocks.

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News Network
December 7,2025

envoy.jpg

Since 1946, the United States has attempted 93 coups or “regime change” operations across the world — including two in Iran, US Special Envoy for Syria Tom Barrack has admitted.

Speaking to the UAE-based IMI Media Group, in remarks published by The National, Barrack said Washington tried twice to overthrow the Iranian government but failed both times. 

“For (Trump) then to be imputed with regime change — we had two regime changes in Iran already. Neither one worked. So I think wisely leave it to the region to solve,” said Barrack, who also serves as the US ambassador to Turkey.

His comments come six months after the US joined Israel in airstrikes against Iran during ongoing indirect nuclear negotiations between Tehran and Washington.

On June 13, Israel launched an attack on Iran that killed at least 1,064 people and hit civilian infrastructure. Days later, the United States targeted three nuclear facilities — Fordow, Natanz and Isfahan — in what Iran called a clear violation of international law. Iranian retaliation eventually forced a halt to the assault on June 24.

Barrack further claimed that US President Donald Trump and Foreign Secretary Marco Rubio are “not into regime change” and prefer a regional approach driven by Middle Eastern countries themselves. According to him, regional dialogue and non-interference by outside powers offer a more durable path forward.

He added that Washington is still open to an agreement with Tehran if Iranian authorities show “seriousness” and willingness to engage constructively.

However, Iran maintains the US has not shown readiness for meaningful talks. In an interview with Japan’s Kyodo News, Iranian Foreign Minister Abbas Araghchi said negotiations could advance only if Washington acknowledges Iran’s right to peaceful nuclear energy and lifts unilateral sanctions.

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News Network
December 2,2025

A major upgrade in safety and monitoring is planned for Haj 2026, with every Indian pilgrim set to receive a Haj Suvidha smart wristband linked to the official Haj Suvidha mobile app. The initiative aims to support pilgrims—especially senior citizens—who may struggle with smartphones during the 45-day journey.

What the Smart Wristband Will Do

Officials said the device will come with:
•    Location tracking
•    Pedometer
•    SOS emergency button
•    Qibla compass
•    Prayer timings
•    Basic health monitoring

SP Tiwari, secretary of the UP State Haj Committee, said the goal is to make the pilgrimage safer and more comfortable.

“Most Hajis are elderly and not comfortable with mobile apps,” he said. “The smartwatch will help locate pilgrims who forget their way or cannot communicate their location.”

The wristbands will be monitored by the Consulate General of India in Saudi Arabia, similar to mobile tracking via the Haj Suvidha App.

Free Distribution and Training

•    Smart wristbands will be given free of cost.
•    Training for pilgrims will be conducted between January and February 2026.
•    Sample units will reach state Haj committees soon.
•    Final devices will be distributed as pilgrims begin their journey.

New Rules for Accommodation

Two major decisions have also been finalised for Haj 2026:
1.    Separate rooms for men and women – including married couples. They may stay on the same floor but must occupy different rooms, following stricter Saudi guidelines.
2.    Cooking banned – gas cylinders will not be allowed; all meals will be provided through official catering services arranged by the Haj Committee of India.

These decisions were finalised during a meeting of the Haj Committee of India and state representatives in Mumbai.

Haj Suvidha App Launched Earlier

The government launched the Haj Suvidha App in 2024, offering:

•    Training modules
•    Accommodation and flight details
•    Baggage information
•    SOS and translation tools
•    Grievance redressal

Haj 2026 Quota and Key States

•    India’s total Haj quota for 2026: 1,75,025 pilgrims
•    70% (1,25,000) allotted to the Haj Committee of India
•    30% (around 50,000) reserved for Haj Group Organisers

Uttar Pradesh has the largest allocation (around 30,000 seats), though approximately 18,000 pilgrims are expected to go this year. States with high pilgrim numbers include Kerala, Maharashtra and Gujarat.

Dates of Haj 2026

The pilgrimage is scheduled to take place from 24 May to 29 May, 2026 (tentative).
Haj is one of the five pillars of Islam and is mandatory for Muslims who meet the required conditions.

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