2 covid vaccines show 'promising immune response' in human trials

News Network
July 20, 2020

Paris, Jul 20: Two coronavirus vaccine candidates have proven safe for humans and produced strong immune reactions among patients involved in separate clinical trials, doctors said on Monday.

The first trial among more than 1,000 adults in Britain found that the vaccine induced "strong antibody and T cell immune responses" against the novel coronavirus.

A separate trial in China involving more than 500 people showed most had developed widespread antibody immune response.

The studies, published in The Lancet medical journal, constitute a major step on the road towards a COVID-19 vaccine that is effective and safe for widespread use.

The authors of the studies said that they encountered few adverse side-effects from the vaccine candidates.

However, they cautioned that more research was needed, particularly among older adults, who are disproportionately at risk of dying of COVID-19.

Co-author Sarah Gilbert from the University of Oxford said the results "hold promise".

"If our vaccine is effective, it is a promising option as these types of vaccine can be manufactured at large scale."

Comments

Add new comment

  • Coastaldigest.com reserves the right to delete or block any comments.
  • Coastaldigset.com is not responsible for its readers’ comments.
  • Comments that are abusive, incendiary or irrelevant are strictly prohibited.
  • Please use a genuine email ID and provide your name to avoid reject.
News Network
September 16,2020

Yoshihide.JPG

Tokyo, Sept 16: Japan's parliament on Wednesday elected Yoshihide Suga prime minister, with the former chief cabinet secretary expected to stick closely to policies championed by Shinzo Abe during his record-breaking tenure.

"According to the results, our house has decided to name Yoshihide Suga prime minister," lower house speaker Tadamori Oshima told parliament after the votes were counted.

Suga, 71, won an easy victory, taking 314 votes of 462 valid ballots cast in the lower house of parliament, where his ruling Liberal Democratic Party holds a commanding majority with its coalition partner.

He bowed deeply as lawmakers applauded following the announcement, but made no immediate comment.

He is expected to announce his cabinet later Wednesday, with local media reporting he will retain a number of ministers from Abe's government.

Suga has said he will prioritise keeping coronavirus infections under control and kickstarting Japan's economy, and has promised to continue Abe's key policy programmes.

Comments

Add new comment

  • Coastaldigest.com reserves the right to delete or block any comments.
  • Coastaldigset.com is not responsible for its readers’ comments.
  • Comments that are abusive, incendiary or irrelevant are strictly prohibited.
  • Please use a genuine email ID and provide your name to avoid reject.
Agencies
September 15,2020

bill.jpg

Washington, Sept 15: Billionaire philanthropist Bill Gates has said India's willingness to play a "big role" in manufacturing Covid-19 vaccine and allow it to supply to other developing countries will be a critical part in containing the coronavirus pandemic globally.

In an exclusive interview to PTI, Gates, whose foundation is focusing on fighting the pandemic, called it the "next biggest thing" the world has been confronted with after the World War.

The Microsoft co-founder said the world is looking to India for large scale production of Covid-19 vaccine once it is rolled out.

"Obviously, all of us want to get a vaccine out in India as fast as we can, once we know that it's very effective and very safe, and so the plans are coming into focus that sometime next year, it's very likely that roll-out will take place and take place in fairly big volume," he said.

"The world is also looking to India for some of that capacity to be available to other developing countries. Exactly what that allocation formula looks like will have to be figured out," Gates added.

Scientists and pharmaceutical companies globally are racing against time to find a vaccine for the coronavirus pandemic which has killed about 9,32,000 people and infected around 24 million. Some of the vaccine candidates have entered the third and final phase of testing.

"This is not like a world war, but it's the next biggest thing after that that we've ever had," he said.

The Bill and Melinda Gates Foundation, one of the world's largest charities, has been involved in global efforts to contain the pandemic. In India, the foundation has entered into a partnership with the Serum Institute to accelerate the manufacturing and delivery of Covid-19 vaccines.

"India's willingness to play a big role in the manufacturing and to allow some of those vaccines to go to other developing countries will be an absolutely critical part of that," said Gates.

"India will be helping to make sure we have equity. We have a model that shows that getting the vaccine out to those who need it the most will save half the lives that you'd lose if you only send it out to the rich countries," he said.

In the telephonic interview, the Microsoft co-founder who has donated billions of dollars to fight poverty and diseases, talked extensively about India's strength in production of vaccines and referred to companies like Serum Institute, Bio E and Bharat Biotech.

"We've been brokering the idea of taking a vaccine and manufacturing it in India, even if it comes from AstraZeneca, Oxford or Novavax or Johnson & Johnson. We've publicly talked about the arrangement where a Serum will be able to make very high volume of the AstraZeneca and the Novavax vaccine," said Gates.

"There's discussions with Bio E, their connection with the Johnson & Johnson vaccine, and whether they'll be able to ramp that up," he said.

Gates also said that the foundation has been having "great discussions" with India's NITI-Aayog, adding the ICMR is looking at the regulatory aspects of the Covid-19 vaccines.

"I'm actually very impressed with how our discussions with the government on these issues and the companies, including the Western companies collaborating with these new companies, that's all gone very well," Gates said.

The American business magnate said he was optimistic that by the first quarter of next year, that several of these vaccines will reach the phase three emergency licence approval.

"We still could be disappointed in that. But we have a variety of constructs and the early data from the phase one and phase two, for example the antibody levels, looks pretty promising for quite a few of these vaccines," he said.

He said the focus should be to keep the cost of the vaccines low and it should be ensured that they can be made in very high volume.

"We have to remember that even once a vaccine is approved, the bar for that vaccine in terms of the effectiveness was set as 50 per cent, and so we still may want to continue with other vaccines to get higher effectiveness," he said.

Gates also complimented India's digital cash transfer scheme.

"Getting payments out through digital cash transfers, that has been a fantastic thing, and obviously, India has done that at a scale that no other country ever has," he said.

"The whole Aadhaar digital financial system in India has proven to be once again a huge asset," he said, adding it can be extended to all the countries of the world.

The philanthropist also referred to the foundation's annual Goalkeepers report saying it normally takes stock of the ongoing progress on things like economic growth, literacy, child survival and average lifespan.

"This year's report, unfortunately, we're unable to say that there's been progress. In fact, we talk about the setback, and one way we dimensionalise that for like vaccine coverage globally, which went from 84 per cent to 70 per cent, is we say that's a 25-year setback," he said.

Asked whether India's economic downturn will impact implementation of social welfare schemes, Gates said the foundation is a huge believer that investments in health pay off very strongly.

"It's tragic that all health activities have been so disrupted, and that will lead to increased deaths from other diseases, not just COVID," he said.

"In fact, in many places, and I'm not sure if India will be included in this, but there's a chance that there would be more deaths from other diseases because of the health disruption than from COVID itself," he said.

Comments

Add new comment

  • Coastaldigest.com reserves the right to delete or block any comments.
  • Coastaldigset.com is not responsible for its readers’ comments.
  • Comments that are abusive, incendiary or irrelevant are strictly prohibited.
  • Please use a genuine email ID and provide your name to avoid reject.
Agencies
September 26,2020

 

World.jpg

Washington, Sept 27: The overall number of global coronavirus cases has topped 32.7 million, while the deaths have increased to more than 992,000, according to the Johns Hopkins University.

As of Sunday morning, the total number of cases stood at 32,746,134 and the fatalities rose to 992,946, the University's Center for Systems Science and Engineering (CSSE) revealed in its latest update.

The US is the worst-hit country with the world's highest number of cases and deaths at 7,077,450 and 204,485, respectively, according to the CSSE.

ndia comes in the second place in terms of cases at 5,903,932, while the country's death toll soared to 93,379.

The other top 15 countries with the maximum amount of cases are Brazil (4,717,991), Russia (1,138,509), Colombia (806,038), Peru (794,584), Mexico (726,431), Spain (716,481), Argentina (702,484), South Africa (669,498), France (552,454), Chile (455,979), Iran (443,086), the UK (431,816), Bangladesh (357,873), Iraq (345,969) and Saudi Arabia (332,790), the CSSE figures showed.

Brazil currently accounts for the second highest number of fatalities at 141,406.

The countries with a death toll above 10,000 are Mexico (76,243), the UK (42,060), Italy (35,818), Peru (32,037), France (31,675), Spain (31,232), Iran (25,394), Colombia (25,296), Russia (20,140), South Africa (16,376), Argentina (15,543), Chile (12,591), Ecuador (11,236) and Indonesia (10,308).

donesia (10,218).

Comments

Add new comment

  • Coastaldigest.com reserves the right to delete or block any comments.
  • Coastaldigset.com is not responsible for its readers’ comments.
  • Comments that are abusive, incendiary or irrelevant are strictly prohibited.
  • Please use a genuine email ID and provide your name to avoid reject.