Kerala doctors detect at least 7 cases of dangerous neuro disorder among Covishield recipients

News Network
June 24, 2021

At least seven cases of Guillain-Barre syndrome – a rare neurological disorder – have been detected by the doctors in Kerala within a month among 12 lakh people who received the Covishield vaccine, prompting them to alert others to watch out for GBS among the vaccine recipients.

“Overall, our experience should prompt all physicians to be vigilant in recognising GBS in patients who have received the ChAdOx1-S vaccine (Covishield in India). While the risk per patient (5.8 per million) may be relatively low, our observations suggest that this clinically distinct GBS variant is more severe than usual and may require mechanical ventilation,” they reported in the Annals of Neurology.

GBS is a rare condition in which the immune system attacks the nerves. The symptoms start as weakness and tingling in the feet and legs. The sensations can quickly spread to the upper body, leading to paralysis in the worst cases.

While the condition may be triggered by an acute bacterial or viral infection, there are treatments available to deal with such medical emergencies.

Out of the seven patients detected by the Kerala doctors, six are women and all of them are 50-70 years of age. They are from Ernakulam, Kottayam and Kannur districts of Kerala where approximately 1.2 million individuals had received the Covishield vaccine as of April 22.

“GBS following vaccination is a rare adverse effect that is likely to be causal. All the seven patients are alive and getting better with treatment,” Boby V Maramattom, the corresponding author of the study and a senior doctor at the department of neurology, Aster Medcity at Kochi said.

The incidence of GBS in India is approximately 6–40 cases per million per year, with a seasonal variation, peaking in the rainy season.

With a denominator of 1.2 million people, the expected cases of GBS per year are approximately seven to 48 annually or between 0.58 to four cases in every four weeks. The reporting of seven GBS cases in 1.2 million people within four weeks (mid March to mid April) marks a 1.4-to-10 fold rise in the incidence of GBS.

“Although the (causative) factors are not completely established, molecular mimicry between viral proteins and human nerve proteins are likely to be a reason,” he said. “It is not completely unexpected with a vaccination but the risk is approximately less than five per million doses.”

A separate team of researchers also reported four such cases from Nottingham in England, an area in which approximately 7,00,000 people received the same vaccine. The frequency of GBS in both the areas was estimated to be up to 10 times greater than expected.

"If the link is causal it could be due to a cross-reactive immune response to the SARS-CoV-2 spike protein and components of the peripheral immune system. The clinicians should be vigilant in looking for this rare neurological syndrome following the administration of Covid-19 vaccines," wrote the authors of the UK report.

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News Network
October 1,2021

Bihar's main opposition party RJD on Friday mocked Kanhaiya Kumar's induction into the Congress, saying that the former JNU student is like "another Navjot Singh Sidhu" who would "destroy" the grand old party.

Ridiculing the Congress by calling it a sinking ship, senior RJD leader Shivanand Tiwari said that Kumar's joining won't make any difference to the party.

Referring to the CPI turncoat's statement that "Congress is a big ship that needs to be saved", Tiwari said, "He is just like another Navjot Singh Sidhu who will further destroy the party."

"Kanhaiya Kumar's induction won't make any difference. He can't save the party. Congress is a sinking ship and it has no future," the RJD leader told reporters.

RJD sources said that the party is unhappy with the fact that Kumar was inducted into the Congress without consulting the Tejashwi Yadav-led party.

The Congress is a part of the RJD-led opposition alliance Mahagathbandhan that fought the 2020 Bihar assembly elections against the NDA.

Bihar Congress leaders declined to comment on the matter.

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News Network
October 11,2021

Kalaburgi, Oct 11: People living in and around Chincholi in Kalaburagi district woke up to a mild earthquake of 2.5 magnitude on the richter scale, barely 24 hours after the first jolt was felt. However, there was no loss of life or damage to any property, officials said.

The quake hit Gadikeshwar village and its surrounding areas, where people panicked and rushed out of their homes, they said.

According to the Karnataka State Natural Disaster Monitoring Centre, the epicentre was Maniyarpalli village in Sangareddy district in Telangana, which is located "very close to Karnataka".

"The epicentre was 1.9 km North East of Shivarampur village in Chincholi Taluk of Kalaburagi," the KSNDMC said in a statement. This is the fourth tremor in the North Karnataka region in the last 11 days. The first two tremors on October 1 and 5 occurred near Basavakalyan in Bidar district, which is in a close proximity to Latur and Killari in neighbouring Maharashtra, which had faced the worst earthquake in September 1993 killing several people.

It is learnt that the Kalaburagi district administration has written to the Mines and Geology Department to study the spate of tremors in the region. 

Already the Karnataka Mineral Administration department has instructed its geologists to study the phenomena and ascertain whether there was any disturbed area in terms of geological events in the past. The department has also decided to carry out awareness drive to deal with a situation in the event of some major untoward incident.

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News Network
October 1,2021

India has registered 26,727 new Covid-19 cases in the last 24 hours, which is 13.6 per cent higher than yesterday. With this, the country's case tally has touched 3,37,66,707.

The daily case count on Thursday was 23,529, which was 24.7 per cent higher than what was recorded on Wednesday.

As many as 277 deaths were reported in the country in the last 24 hours, increasing the total death count to 4,48,339, according to the latest data released by the Union Health Ministry.

- The top five states which have registered maximum cases are Kerala with 15,914 cases, followed by Maharashtra with 3,063 cases, Tamil Nadu with 1,612 cases, Mizoram with 1,170 cases and Andhra Pradesh with 1,010 cases.

-At least 85.19 per cent of the new cases are reported from these five states, with Kerala alone responsible for 59.54 per cent of the new cases.

-277 deaths were reported in the country in the last 24 hours, increasing the total reported death count to 4,48,339.

-Maximum casualties were reported in Kerala (122), followed by Maharashtra with 56 daily deaths.

-India's recovery rate now stands at 97.86 per cent.

-A total of 28,246 patients recovered in the last 24 hours, which brings the total recoveries to 3,30,43,144 across the country.

-India's active caseload stands at 2,75,224. In the last 24 hours, active cases declined by 1,796.

-India has administered a total of 64,40,451 doses in the last 24 hours, which brings the total tally of doses administered to 89,02,08,007.

-A total of 15,20,899 samples were tested in the last 24 hours.

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