Novel vaccine proven effective against Zika virus

Agencies
August 8, 2018

Washington, Aug 8: A uniquely designed experimental vaccine against Zika virus has proven powerful in mice, scientists have found, paving the way for preventing the infection that causes babies to develop serious birth defects.

The vaccine, developed by researchers at Ohio State University in the US employs an uncommon two-pronged approach to fighting the virus, which is spread by mosquitoes and is most serious for pregnant women and their foetuses.

The single-dose vaccine, carrying the genes for two or three Zika proteins, proved effective in triggering an immune response that prevented later infection by Zika virus, researchers said.

"In this study, the vaccine was potent, safe and highly effective, at least in the short term. There's a long way to go, but we think this is a promising candidate for a human vaccine," said Jianrong Li, a professor at Ohio State, who led the study published in the journal Nature Communications.

Babies born to Zika-infected mothers are sometimes born with a birth defect called microcephaly.

Other complications include miscarriage, stillbirth and other birth defects. Research also suggests that a small percentage of people infected with the virus can contract Guillain-Barre syndrome, which affects the nervous system.

There's no vaccine available currently and the only protection against Zika are preventative measures such as insect repellant, staying indoors and wearing long sleeves and pants.

Shan-Lu Liu, a study co-author from Ohio State, said the experimental vaccine holds particular promise because it appears to afford an adequate immune response with one dose.

In hard-to-reach and resource-poor areas, that becomes especially valuable, he said.

The study included experiments in mice with severely compromised immune systems - a necessary step to make sure that mice could get sick after infection with Zika virus.

When the vaccinated mice were exposed to Zika virus, their weak immune systems fought it off swiftly and efficiently, convincing the research team that their design had worked.

The early success with this vaccine has encouraged this team to use the same approach to fight other related viruses, including dengue fever, the researchers said.

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News Network
May 17,2024

Forbes has released its ninth edition of the “30 Under 30 Asia” list, celebrating 300 young entrepreneurs, leaders, and trailblazers under 30 who are driving innovation and transforming industries across the Asia-Pacific region. 

Here's a list of Indians who made it to the Forbes list:

ENTERTAINMENT

Pavithra Chari
Pavithra Chari, a trained singer-composer, gained recognition as half of the duo Shadow and Light with Anindo Bose. Their collaboration with the Berklee Indian Ensemble earned a Grammy nomination in 2023. She is also part of the Anirudh Varma Collective, touring the US, and is skilled in Bharatnatyam dance. Ms Chari is also known for covering film hits.

Arpan Kumar Chandel (King)
Indian rapper Arpan Kumar Chandel, also known as King, became known worldwide when Nick Jonas remixed his hit song 'Maan Meri Jaan'. Mr King got famous on MTV Hustle in 2019 and has released many albums since. His latest, 'New Life', features artists like Nikhita Gandhi and Gucci Mane. He's also Sony Audio's ambassador and launched his fragrance, Blanko.

CONSUMER TECHNOLOGY

Kush Jain 
Kush Jain discovered the challenges faced by the visually impaired during a volunteering stint at a Bangalore school in 2018. Motivated to help, he co-founded ORama AI. Their innovative solution, a smart glove, helps the blind and those with reduced vision to learn Braille. The glove features an embedded camera and speaker, tracking finger movements and audibly identifying touched Braille dots.

Arth Chowdhary, Deyvant Bhardwaj and Oshi Kumari 
Arth Chowdhary, Deyvant Bhardwaj and Oshi Kumari co-founded InsideFPV, an Indian drone startup, in 2020. Their main product is an easy-to-use "plug-and-fly" drone, unlike others that require a complex setup. Based in Surat, the company also sells drones and parts online. 

Pranav Manpuria (Flux Auto)
Autonomous driving startup Flux Auto was co-founded by Pranav Manpuria in 2017. The company is working on creating self-driving software for forklifts and warehouse robots. They claim their technology can easily fit into existing systems of infrastructure.

Arun Sreyas and Gautham Maheswaran (RACE Energy)
In 2018, university friends Arun Sreyas and Gautham Maheswaran created RACE Energy. Headquartered in Hyderabad, the startup specialises in creating swappable battery packs tailored for the popular three-wheeled auto-rickshaws in India.

Harshit Jain and Abhik Saha 
Harshit Jain and Abhik Saha co-founded OnePlay, a cloud gaming startup in Mumbai in 2019. OnePlay allows users to play popular games like Baldur's Gate 3 and Palworld across multiple platforms without needing expensive hardware. 

ENTERPRISE TECHNOLOGY

Kunal Aggarwal
Kunal Aggarwal launched Credflow in 2019, offering cashflow management software for small and medium-sized enterprises. The platform analyses business data, sends automated payment reminders, and extends credit lines to eligible users. 

Gaurav Piyush, Mayank Varshney and Yash Sharma
Gaurav Piyush, Mayank Varshney and Yash Sharma came together to establish Blitz, a logistics startup, in 2020. Based in Gurugram, the company, formerly known as Grow Simplee, specialises in offering same- or next-day delivery services by using a network of warehouses and fulfilment centres.

Aditya Dadia
Aditya Dadia founded AIwrite in 2022, providing new digital software for India's insurance sector. Based in Mumbai, the startup uses machine learning to help insurance companies analyze risks and develop products faster. 

FINANCE AND VENTURE CAPITAL

Aalesh Avlani (CWC)
Aalesh Avlani, a Boston University graduate, co-founded Credit Wise Capital (CWC), a finance company specialising in providing loans for motorcycles. Founded in 2019, CWC received $6 million in startup funding the following year. They use technology like a WhatsApp bot to quickly assess creditworthiness, making it easier for people with no credit history to apply for loans.  

Srinivas Sarkar and Kushagra Manglik (Coupl)
Srinivas Sarkar and Kushagra Manglik co-founded Coupl, India's bank designed for couples of all types. Launched in early 2022, the startup helps couples, irrespective of marital status or sexual orientation, effectively manage their finances with joint accounts and linked ATM cards.

Aniket Damle
Aniket Damle works with Blackstone's private equity investment team in Asia, focusing on investments in India's healthcare, consumer, and industrial sectors. At just 23 years old, he made his first deal when Blackstone collaborated with Sona BLW to establish Sona Comstar, a technology platform company focused on electric vehicles, in 2018.

Yashvardhan Kanoi (Alter Global)
Yashvardhan Kanoi heads investments at Alter Global, a venture capital firm linking Silicon Valley with startups in emerging markets. Since 2019, he led investments in companies across Southeast Asia, South Asia, and Latin America like Ula, BukuKas, and CoLearn.

Manish Maryada (Fello)
Manish Maryada co-founded Fello, a fintech startup based in India. Fello offers rewards to users to make investing enjoyable. When users invest a certain amount through the app, they receive a ticket to play in-house games and win rewards and prizes. Founded in 2021, Fello has been downloaded over a million times and has raised over $5 million in funding.

Anuj Srivastava and Priyesh Srivastava (OnFinance AI)
Anuj Srivastava and Priyesh Srivastava (not related) co-founded OnFinance AI, a Bengaluru-based startup. They developed NeoGPT, a ChatGPT-like service tailored for the finance industry, which helps analyse data, generate forecasts, and conduct financial market research.

HEALTHCARE AND SCIENCE

Karan Ahuja
Google research scientist Karan Ahuja will become an assistant professor of computer science at Northwestern University starting in September 2024. With a PhD in human-computer interaction from Carnegie Mellon University, Mr Ahuja has focused on projects like body-movement sensing for smartwatches and gaze-tracking for smartphone control. His work has earned nearly 1,000 citations over the past five years. 

Aryan Chauhan
Aryan Chauhan, along with his mother Monika Chauhan, co-founded Zivov in 2021 with the aim of helping with diabetes treatment. Their solution involves a self-developed sensor that attaches to the skin to monitor blood sugar levels. Users can access the results through Zivov's smartphone app.

INDUSTRY, MANUFACTURING AND ENERGY

Akshit Bansal and Raghav Arora (Statiq)
Akshit Bansal, CEO of Statiq, got the idea for greener transportation while biking through Bengaluru's polluted streets. After a failed car-sharing venture with his friend Raghav Arora, they shifted their focus to electric vehicles. Their Gurgaon-based company, Statiq, now operates a nationwide network of charging stations for electric cars, buses, trucks, and three-wheelers. The company has raised $27.5 million from investors and expects to post its first operating profit in the next financial year.

Ankit Jain and Narayan Lal Gurjar (EF Polymer)
Ankit Jain and Narayan Lal Gurjar co-founded the agriculture startup EF Polymer in 2018. Their company has created a powder-like water-retention product made from biodegradable materials like bananas and orange peels. This product helps retain moisture in the soil and enhance crop yields by absorbing excess water and gradually releasing it.

Chirag Jain and Rama Krishna Mendu (EndureAir Systems)
Chirag Jain and Rama Krishna Mendu founded EndureAir Systems, a drone startup, in 2018. The Noida-based company has created three drone models for mapping, monitoring, and logistics. One of them is battery-powered and can carry up to 15 kg while travelling 15 km.  

Rahil Gupta (Hop Electric Mobility)
Rahil Gupta co-founded Hop Electric Mobility, an electric motorbike startup, in 2020. The company offers three products priced between ₹66,790 and ₹1,33,580. Their premium Oxo bike, for instance, can reach speeds of up to 95 km per hour and cover 150 km on a single charge

MEDIA, MARKETING AND ADVERTISING

Kavan Antani

Kavan Antani is one of the co-founders of IndieFolio, a Mumbai-based on-demand talent marketplace catering to creative professionals. Launched in 2014, the platform serves as a connection hub for designers, animators, content creators, and video producers with clients seeking talent. IndieFolio boasts a talent pool of over 70,000 individuals and counts major clients like Paytm, Ogilvy, and Domino's Pizza.

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News Network
May 12,2024

Mangaluru, May 12: In a shocking development, a group of pilgrims which had travelled from Mangaluru International Airport to Saudi Arabia earlier this month, to perform Umrah has alleged that 26,432 Saudi Riyals, which were kept in a bag, have been stolen. 

In a complaint submitted to the Bajpe Police, Soukath Banu, wife of Ahmed Iqbal of Ajyad Tours and Travels, said that her husband, Ahmed Iqbal, along with 35 members, planned and scheduled to perform the Umrah and were travelling from Mangaluru International Airport (MIA) via Mumbai to Jeddah. 

Soukath Banu had given Ahmed Iqbal 2,000 Saudi Riyals for performing Umrah and other expenses. The group members were also told to bring Saudi Riyals to meet their expenses.

In her plaint, Soukath stated that the group had left for Jeddah on an IndiGo flight via Mumbai, and their return ticket to India was booked for May 13. 

At the airport, she said that 26,432 Saudi Riyals were collected in total, and they decided to keep them in baggage that had a lock. Accordingly, it was kept in the bag of Mohammad Badruddin Kadambar. The airport staff had even questioned what he had kept in the bag. 

The group reached Jeddah on May 1. To their surprise, Kadambar found that the baggage lock was broken open, the zip was damaged, and cash was stolen upon reaching Jeddah.

DCP (Law and Order) Sidharth Goyal said that following the complaint, one round of CCTV checks was conducted at the MIA along with the CISF personnel. The loading at the MIA was intact.

Further checks have to be carried out at Mumbai and Jeddah Airport as the victim found out that cash was missing only when they got the bag at the final destination, he added.

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News Network
May 8,2024

Mangaluru: The Mangaluru North police have apprehended a minor in connection with alleged voyeurism incident reported in a private medical college in Mangaluru. 

DCP (Law and order) Sidharth Goyal said that the minor was produced before JJ Board as per due procedure. The incident came to light when a mobile phone was found in women's washroom in the college. 

The mobile-phone was discovered as it was ringing even when no one was in the toilet by the security guard of the college. 

Investigations revealed that the mobile phone had been strategically placed in the restroom. As a result, a case has been registered under north police station.

Further scrutiny into the matter uncovered the identity of the accused, a minor male aged 17, who had gained access to the college premises under the guise of being a patient. Following his apprehension, the accused was presented before the Juvenile Justice (JJ) Board in adherence to legal protocols.

The phone has been seized and a case has been booked under IPC section 354 (C), said the DCP.

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