All you need to know about Mosquirix, the 1st malaria vaccine endorsed by WHO

News Network
October 7, 2021

The World Health Organization (WHO) has endorsed Mosquirix, the RTS,S/AS01 malaria vaccine — the first and the only till date — against the mosquito-borne disease that kills more than 400,000 people a year, mostly African children.

The vaccine acts against plasmodium falciparum -- one of five malaria parasite species and the most deadly, most prevalent in Africa. The vaccine’s trial data showed that it could prevent 4 out of 10 malaria cases over a period of four years, when four doses were administered to children. Mosquirix is the first malaria vaccine which has finished its clinical development process.

Mosquirix, is not just a first for malaria; it is the first developed for any parasitic disease. Parasites are much more complex than viruses or bacteria, and the quest for a malaria vaccine has been underway for 100 years.

WHO’s approval followed a review of a pilot programme deployed since 2019 in Ghana, Kenya and Malawi in which more than two million doses were given of the vaccine, first made by the pharmaceutical company GSK in 1987.

In clinical trials, the vaccine had an efficacy of about 50 per cent against severe malaria in the first year, but the figure dropped close to zero by the fourth year. And the trials did not directly measure the vaccine’s impact on deaths, which has led some experts to question whether it is a worthwhile investment in countries with countless other intractable problems.

Malaria research is littered with vaccine candidates that never made it past clinical trials. Bed nets, the most widespread preventive measure, cut malaria deaths in children younger than 5 by only about 20%.

Against that backdrop, the new vaccine, even with modest efficacy, is the best new development in the fight against the disease in decades, some experts said.

How malaria affects the world

Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes.

In 2019, there were an estimated 229 million cases of malaria worldwide and the death toll due to malaria was 4,09,000.

African regions carry a disproportionately high share of the global malaria burden. In 2019, the region was home to 94% of malaria cases and deaths.

How to use the vaccine

WHO has recommended that in the context of comprehensive malaria control, Mosquirix be used for the prevention of P. falciparum malaria in children living in regions with moderate to high transmission. Mosquirix is to be given in three doses between ages 5 and 17 months, and a fourth dose roughly 18 months later. 

Funds for the programme were mobilised through Gavi, the Vaccine Alliance; the Global Fund to Fight AIDS, Tuberculosis and Malaria; and Unitaid, according to WHO.

The Bill & Melinda Gates Foundation provided catalytic funding for late-stage development of RTS,S between 2001 and 2015.

Germany's BioNTech, which developed a coronavirus vaccine with US giant Pfizer, also said it aimed to start trials for a malaria vaccine next year using the same breakthrough mRNA technology.

The WHO also hopes this latest recommendation will encourage scientists to develop more malaria vaccines.

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News Network
January 19,2026

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Donald Trump has linked his repeated threats to seize Greenland to his failure to win the Nobel Peace Prize, in a letter to Norwegian Prime Minister Jonas Gahr Støre.

The authenticity of the letter, in which Trump says he no longer feels obligated to “think purely of peace,” was confirmed by Støre to the Norwegian newspaper VG.

“Considering your country decided not to give me the Nobel Peace Prize for having stopped eight wars plus, I no longer feel an obligation to think purely of peace,” Trump wrote, adding he can now “think about what is good and proper for the United States.”

Støre said Trump’s letter was in response to a short message he had sent earlier, on behalf of himself and Finland’s President Alexander Stubb.

Trump has escalated rhetoric toward Greenland, a self-governing Danish territory, insisting the US will take control “one way or the other.” Over the weekend, he tweeted: “Now it is time, and it will be done!!!”

On Saturday, Trump threatened a 10% tariff on imports from Denmark, Norway, Sweden, France, Germany, the UK, the Netherlands, and Finland from 1 February until the US is allowed to purchase the island. EU diplomats met for emergency talks on possible retaliatory tariffs and sanctions.

In his letter, Trump argued Denmark “cannot protect” Greenland from Russia or China, questioning Danish ownership: “There are no written documents; it’s only that a boat landed there hundreds of years ago.” He added that NATO should support the US, claiming the world is “not secure unless we have complete and total control of Greenland.”

Trump’s stance has unsettled the EU and NATO, as he refused to rule out military action to take control of the mineral-rich island.

The Nobel Peace Prize is awarded by the independent Norwegian Nobel Committee, not the government. Trump had campaigned for last year’s prize, which went to Venezuelan opposition leader María Corina Machado, who dedicated her award to him.

Støre reiterated that the Nobel Prize decision rests solely with the committee.

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News Network
January 20,2026

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KCF, a global socio-cultural organisation of Karnataka expatriates, is actively involved in education, humanitarian initiatives and community well-being across several countries. The awardees were selected following a structured evaluation of nominations by the Annual Council Program Committee, based on the depth, consistency and long-term impact of their social service.

One of the award recipients, Abdul Razak Haji, a prominent UAE-based entrepreneur from the Qamcon Group of Companies, was honoured for his significant contributions to society. Through both his professional journey and personal initiatives, he has supported numerous employees and families, while also extending assistance in education, housing for the underprivileged and various charitable causes, largely carried out quietly over the years. His award was presented earlier during the Annual Council Program held at the KCF Abu Dhabi office.

The second award was conferred on Latheef Kakkinje, a young social worker based in Abu Dhabi, in recognition of his active involvement in community engagement programmes, sports initiatives, talent festivals and family-oriented social activities. His consistent volunteering efforts and commitment to humanitarian causes were highly appreciated by the selection committee.

The award presentation ceremony for Latheef Kakkinje was held at the Zayed Cricket Stadium (Astro Turf Ground) in the presence of Kedumbady Ibrahim Saqafi, President of KCF UAE; Ibrahim, General Secretary; Kabeer Bayambady, President of KCF Abu Dhabi; Ummer Ishwaramangila, General Secretary; along with other members of the KCF Abu Dhabi cabinet.

Congratulating both awardees, KCF leaders reiterated the organisation’s commitment to recognising individuals who selflessly work for social upliftment and community service.

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coastaldigest.com news network
January 19,2026

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Bengaluru: As the dust settles on the recent legislative session, the corridors of Vidhana Soudha are buzzing with more than just policy talk. A high-stakes game of political musical chairs has begun, exposing a deepening rift within the Congress party’s Muslim leadership as a major Cabinet reshuffle looms.

With the party hierarchy signaling a "50% refresh" to gear up for the 2028 Assembly elections, the race to fill three projected Muslim ministerial berths has transformed from a strategic discussion into an all-out turf war.

The "Star Son" Spark

The internal friction turned public this week following provocative remarks by Zaid Khan, actor and son of Wakf Minister Zameer Ahmed Khan. Zaid’s claim—that his father "helped" secure a ticket for Shivajinagar MLA Rizwan Arshad in 2023—has acted as a lightning rod for resentment.

Rizwan’s camp was quick to fire back, dismissing the comment as a desperate attempt by Zameer to manufacture seniority. "Rizwan’s political pedigree was forged in the NSUI and Youth Congress long before Zameer even stepped into the party," a supporter noted, highlighting Rizwan’s tenure as an AICC secretary and his two-term presidency of the State Youth Congress.

A Tale of Two Loyalists

While both Zameer Ahmed Khan and Rizwan Arshad are staunch allies of Chief Minister Siddaramaiah and represent Bengaluru strongholds, their political DNA could not be more different:

•    Zameer Ahmed Khan: A four-time MLA who crossed over from JD(S) in 2018. Known for his "overzealous" and often polarizing outreach during communal flashpoints—from the DJ Halli riots to the recent Wakf land notice controversy—his style has frequently left the Congress high command in a state of "discomfort."

•    Rizwan Arshad: A homegrown organizational man. Seen as a "quiet performer," Arshad represents the sophisticated, moderate face of the party, preferred by those who find Zameer’s brand of politics too volatile.

The Outsiders Looking In

The bickering isn't limited to a duo. The "Beary" community, represented by leaders like N A Haris and Saleem Ahmed, is demanding its pound of flesh. Saleem Ahmed, the Chief Whip in the Legislative Council, has dropped the veil of diplomacy, openly declaring his ministerial aspirations.

"I was the only working president not included in the Cabinet last time," Saleem noted pointedly, signaling that the "loyalty quota" is no longer enough to keep the peace.

As Chief Minister Siddaramaiah prepares to finalize the list, he faces a delicate balancing act: rewarding the aggressive grassroots mobilization of Zameer’s camp without alienating the organizational stalwarts and minority sub-sects who feel increasingly sidelined by the "Chamarajpet-Shivajinagar" binary.

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