World's 1st IVF baby born using new embryo screening technique

July 8, 2013

IVF_baby
London, Jul 8: A healthy boy in the US has become the world's first test tube baby to be born using a new low cost "next-generation sequencing" IVF technique that screens the embryo for genetic defects, Oxford scientists announced today.

The method, through which the baby was born last month, uses the latest DNA sequencing techniques and aims to increase in-vitro fertilisation success rates while being more affordable for couples and lowering the risk of miscarriages, researchers say.

The international team led by Dr Dagan Wells of Oxford University showed how "next-generation sequencing" can be used to pick the embryos created by IVF that are most likely to lead to successful pregnancies.

The approach can identify embryos with the correct number of chromosomes and may cut hundreds of pounds off the cost of embryo screening, Wells said.

The majority of embryos produced by IVF aren't able to lead to successful pregnancies, and scientists have sought to find ways of identifying the embryos that should be implanted to give the greatest chance of success.

Having an incorrect number of chromosomes usually prevents embryos from producing a pregnancy. Until recently, such abnormalities have been hard to detect as they do not affect the appearance of embryos under the microscope.

"Many of the embryos produced during infertility treatments have no chance of becoming a baby because they carry lethal genetic abnormalities," Wells, said. "Next-generation sequencing improves our ability to detect these abnormalities and helps us identify the embryos with the best chances of producing a viable pregnancy. Potentially, this should lead to improved IVF success rates and a lower risk of miscarriage," he said.

Recently, a number of trials of various chromosome screening methods have shown that they can improve IVF success rates by around 30 per cent. But the costs of these genetic tests remain a barrier to their widespread use.

This led Wells and colleagues to look at the possibilities of using the latest in DNA sequencing technology to screen embryos for chromosomal abnormalities.

"Results from randomised clinical trials carried out during the last year have suggested that most IVF patients would benefit from embryo chromosome screening. However, the costs of these genetic tests are relatively high, putting them beyond the reach of many patients. Next-generation sequencing could make chromosome testing more widely available, improving access by cutting the costs," Wells said.

The researchers' approach involves sequencing DNA from multiple embryos all at the same time. Short DNA tags or 'barcodes' added to the genetic material from each individual embryo mean that the results could be identified uniquely and mapped back to the right embryo.In the future, it should be possible to use the approach to check for chromosomal abnormalities and any serious inherited disorders at the same time, researchers said.

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News Network
December 19,2025

Mangaluru: Public transport in Mangaluru is set for a state-led transformation as the government moves to deploy 100 new electric govt buses to replace unreliable private services. The initiative aims to provide a dependable alternative to private operators who have been frequently "cutting trips," leaving thousands of commuters stranded.

The announcement was made by Deputy Commissioner and MCC Administrator Darshan HV during a public phone-in session. The move specifically targets routes where private bus service has become erratic, ensuring that citizens no longer have to rely on a fluctuating private sector for their daily commute.

Restoring the Govt Presence

The transport crisis was brought to the forefront by Ramayya, a resident of Bajal, who highlighted a growing trend of private buses skipping morning and night trips. With the previous KSRTC (govt) services discontinued, residents have been left without a fallback option.

To fix this, the DC confirmed that the PM-eBus Sewa Scheme will bring 100 government-owned electric buses to the city:

•    Phased Deployment: The first 50 of the new 100 government buses are scheduled to arrive by March 2026.

•    State Infrastructure: Two new government depots, including one at Mudipu, are being prepared for operations.

•    Recruitment: The state has already begun training a new batch of government bus drivers to ensure the fleet is operational the moment it arrives.

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News Network
December 7,2025

SHRIMP.jpg

Mangaluru, Dec 7: A rare bamboo shrimp has been rediscovered on mainland India more than 70 years after it was last reported, confirming for the first time the presence of Atyopsis spinipes in the country. The find was made by researchers from the Centre for Climate Change Studies at Sathyabama Institute of Science and Technology, Chennai, during surveys in Karnataka and Odisha.

The team — shrimp expert Dr S Prakash, PhD scholar K Kunjulakshmi, and Mangaluru-based researcher Maclean Antony Santos — combined field surveys, ecological assessments and DNA analysis to identify the elusive species. Their findings, published in Zootaxa, resolve decades of taxonomic confusion stemming from a 1951 report that misidentified the species as Atyopsis moluccensis without strong evidence.

The shrimp has now been confirmed at two locations: the Mulki–Pavanje estuary near Mangaluru and the Kuakhai River in Bhubaneswar. Historical specimens from the Andaman Islands, previously labelled as A. moluccensis, were also found to be misidentified and actually belong to A. spinipes.

The rediscovery began after an aquarium hobbyist in Odisha spotted a shrimp in 2022, prompting systematic surveys across Udupi, Karwar and Mangaluru. Four female specimens were collected in Mulki and one in Odisha, all genetically matching.

Researchers warn the species may exist in very small, vulnerable populations as freshwater habitats face increasing pressure from pollution, sand mining and infrastructure development. All verified specimens have been deposited with the Zoological Survey of India for future reference.

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News Network
December 15,2025

Mangaluru, Dec 15: Air India Express has announced that it will resume direct flight services between Mangaluru and Muscat from March 2026, restoring an important international air link for passengers from the coastal region.

Airport authorities said the service will operate twice a week—on Sundays and Tuesdays—from March 1. The initial flights are scheduled on March 3, 8 and 10, followed by March 15 and 17, with the same operating pattern to continue thereafter. The flight duration is approximately three hours and 25 minutes.

The Mangaluru–Muscat route was earlier operated under the 2025 summer schedule, with services beginning on July 14. At that time, Air India Express had operated four flights a week before suspending the service.

Officials said the summer schedule will come into effect from March 29, after which changes in flight timings and departure schedules from Mangaluru are expected. Passengers have been advised to check the latest schedules while planning their travel.

The resumption of direct flights to Muscat is expected to significantly benefit expatriates, business travellers and others, further strengthening Mangaluru’s air connectivity with the Gulf region.

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