Tamarind seed protein has potential to cure Chikungunya: IIT-R study

Agencies
November 14, 2018

New Delhi, Nov 14: Two professors at Indian Institute of Technology (IIT) Roorkee claimed to have discovered a protein in tamarind seeds that has anti-viral properties and can potentially be used to develop medication for chikungunya.

The research group at IIT Roorkee has filed a patent for an antiviral composition containing this tamarind antiviral protein and is now developing tamarind-based therapeutic agents for chikungunya.

"Tamarind is known for various medicinal properties in India and is a excellent Ayurvedic food. The fruits, seeds, leaves and roots bark of the tamarind tree have been used to treat abdominal pain, diarrhoea and dysentery, bacterial infections and parasitic infestations, wounds, constipation and inflammation," said one of the professors, Shaily Tomar.

Lectin, a diverse group of proteins derived from plant sources, are known to bind to glycan sugars. Its use as antiviral has been extensively studied for a range of viruses, including HIV and HPV.

The IIT professors, in a study, have shown that a lectin derived from tamarind seeds bind to glycans or sugar molecules having N-acetylglucosamine (NAG) on the capsule of viruses, thereby preventing the entry of the virus into the host cells.

The researchers have isolated lectin from tamarind seeds using chromatography and have studied the binding of the lectin molecules to the glycan in the viral capsule by a process called Enzyme-Linked ImmunoSorbent Assay (ELISA).

"Not only did the chikungunya virus lose 64 per cent of its infectivity on treatment with the lectin, but the levels of viral RNA in the cells were also found to reduce to nearly 45 per cent. This study has, for the first time, evaluated the antiviral use of tamarind seed-derived lectin having specificity for NAG and assessed its ability to block the entry step of the virus," Tomar added.

"Antiviral drugs and vaccines against most alphaviruses, including chikungunya are still not available in the market, and preventive measures are currently the only route to managing diseases caused by such viruses," said professor Pravindra Kumar, who is also part of the research.

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News Network
November 27,2025

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Bengaluru: The Vokkaligara Sangha on Thursday issued a stern warning to the Congress, saying the party could face serious electoral repercussions if Deputy Chief Minister D.K. Shivakumar is not appointed as Chief Minister.

The warning follows the public backing of Shivakumar’s chief ministerial ambition by top Vokkaliga pontiff Nirmalanandanatha Swami, who urged the Congress high command to honor his claim.

“The community supported Congress in the 2023 Assembly elections only because Shivakumar had a real chance to become CM. If he is cheated, we’ll teach the party a big lesson,” said newly elected Sangha president L. Srinivas. He added that Vokkaligas would organize protests under the guidance of community leaders.

General Secretary C.G. Gangadhar pointed out that Congress won more seats in the Vokkaliga-dominated Old Mysuru region due to Shivakumar’s influence, adding, “If Congress wants to retain power, Shivakumar should be made the CM.”

Outgoing president Kenchappa Gowda emphasized Shivakumar’s contribution to Congress’ victory. “Our community voted for Congress thinking he would become CM. Siddaramaiah has also served the party well, but Shivakumar should now be given a chance,” he said.

Former general-secretary Konappa Reddy appealed to Sonia and Rahul Gandhi to recognize Shivakumar’s loyalty and service, saying, “Congress is known to keep its promises. We hope it won’t break the promise made to him.”

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coastaldigest.com news network
November 28,2025

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Udupi district transformed into a sea of saffron and celebration on Friday, November 28, as Prime Minister Narendra Modi’s roadshow swept through the coastal temple town. Thousands of residents lined the streets, turning the event into a vibrant public spectacle filled with cheers, flags, and festive energy.

The procession route—from the helipad to the historic Sri Krishna Math—was decked with buntings, saffron flags, and multilayered security barricades. One of the district’s largest-ever security deployments was put in place for the high-profile visit, with over 3,000 police personnel on duty. The arrangement included ten SPs, 27 DSPs, 49 inspectors, 127 sub-inspectors, 232 assistant sub-inspectors, 1,608 constables, and 39 women staff.

Six platoons of the Karnataka State Reserve Police, six Quick Response Teams, bomb detection units, and dog squads were stationed across Udupi. Enhanced surveillance covered Adi Udupi, Bannanje bus stand, and the Sri Krishna Math parking zone, with combing operations carried out along the roadshow corridor.

At the 800-year-old Sri Krishna Math, preparations reached a ceremonial peak. Paryaya Puttige Math seer Sugunendra Teertha Swamiji said the Prime Minister would take part in the Laksha Kantha Geetha Parayana, a mass chanting of the Bhagavad Gita by one lakh devotees, and inaugurate the new Suvarna Teertha Mantapa.

“He will first offer floral tributes to saint-poet Kanakadasa and then unveil the golden covering over the Kanakana Kindi,” the seer said.

The Prime Minister will also receive a Poorna Kumbha welcome and have darshan of Lord Sri Krishna, Mukhyaprana Devaru, and the Suvarna Paduke. Union Minister Pralhad Joshi, Karnataka Governor Thaawarchand Gehlot, Minister Bairathi Suresh, Dharmadhikari D. Veerendra Heggade, and seers from the Ashta Maths are expected to join the ceremony.

Ahead of his arrival, the Prime Minister posted on X that he felt “honoured” to attend the spiritually significant gathering. “This is a special occasion that brings together people from different sections of society for a recital of the Gita. This Matha has a very special significance in our cultural life,” he wrote, noting the institution’s long-standing legacy rooted in the teachings of Sri Madhvacharya.

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News Network
November 26,2025

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Bengaluru, Nov 26: Karnataka is taking its first concrete steps towards lifting a three-decade-old ban on student elections in colleges and universities. Deputy Chief Minister D.K. Shivakumar announced Wednesday that the state government will form a small committee to study the reintroduction of campus polls, a practice halted in 1989 following incidents of violence.

Speaking at a 'Constitution Day' event organised by the Karnataka Congress, Mr. Shivakumar underscored the move's aim: nurturing new political leadership from the grassroots.

"Recently, (Leader of the Opposition in Lok Sabha) Rahul Gandhi wrote a letter to me and Chief Minister (Siddaramaiah) asking us to think about restarting student elections," Shivakumar stated. "I'm announcing today that we'll form a small committee and seek a report on this."

Student elections were banned in Karnataka in 1989, largely due to concerns over violence and the infiltration of political party affiliates into campus life. The ban effectively extinguished vibrant student bodies and the pipeline of young leaders they often produced.

Mr. Shivakumar, who also serves as the Karnataka Congress president, said that former student leaders will be consulted to "study the pros and cons" of the re-introduction.

Acknowledging the history of the ban, he added, "There were many criminal activities taking place back then. We’ll see how we can conduct (student) elections by regulating such criminal activities."

The Deputy CM reminisced about his own journey, which began on campus. He recalled his political activism at Sri Jagadguru Renukacharya College leading to his first Assembly ticket in 1985 at the age of 23. "That's how student leadership was at the time. Such leadership has gone today. College elections have stopped," he lamented, adding that for many, college elections were "like a big movement" where leaders were forged.

The move, driven by the Congress high command's push to cultivate young talent, will face scrutiny from academics and university authorities who have, in the past, expressed concern that the return of polls could disrupt the peaceful academic environment and turn campuses into political battlegrounds.

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